The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

Sas-6 and Ana2/STIL proteins are required for centriole duplication and the homo-oligomerisation properties of Sas-6 help establish the ninefold symmetry of the central cartwheel that initiates centriole assembly. Ana2/STIL proteins are poorly conserved, but they all contain a predicted Central Coil...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Cottee, Matthew A, Muschalik, Nadine, Johnson, Steven, Leveson, Joanna, Raff, Jordan W, Lea, Susan M
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2015
Schlagworte:
Biophysics and Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471874/
https://ncbi.nlm.nih.gov/pubmed/26002084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07236
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