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Binding of STIL to Plk4 activates kinase activity to promote centriole assembly
Centriole duplication occurs once per cell cycle in order to maintain control of centrosome number and ensure genome integrity. Polo-like kinase 4 (Plk4) is a master regulator of centriole biogenesis, but how its activity is regulated to control centriole assembly is unclear. Here we used gene editi...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477857/ https://ncbi.nlm.nih.gov/pubmed/26101219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201502088 |
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