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p53 protects against genome instability following centriole duplication failure
Centriole function has been difficult to study because of a lack of specific tools that allow persistent and reversible centriole depletion. Here we combined gene targeting with an auxin-inducible degradation system to achieve rapid, titratable, and reversible control of Polo-like kinase 4 (Plk4), a...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4494000/ https://ncbi.nlm.nih.gov/pubmed/26150389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201502089 |
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