WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication

Centriole duplication occurs once in each cell cycle to maintain centrosome number. A previous genome-wide screen revealed that depletion of 14 RNA splicing factors leads to a specific defect in centriole duplication, but the cause of this deficit remains unknown. Here, we identified an additional p...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Park, Elizabeth M., Scott, Phillip M., Clutario, Kevin, Cassidy, Katelyn B., Zhan, Kevin, Gerber, Scott A., Holland, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039186/
https://ncbi.nlm.nih.gov/pubmed/31874114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904203
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