Загрузка...

A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies

A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of PLK4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3) domain of PLK4 and the coiled-coil dom...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Biol Open
Главные авторы: Cottee, Matthew A., Johnson, Steven, Raff, Jordan W., Lea, Susan M.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374404/
https://ncbi.nlm.nih.gov/pubmed/28202467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024661
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!