Efficacy of ALK5 inhibition in myelofibrosis

Myelofibrosis (MF) is a bone marrow disorder characterized by clonal myeloproliferation, aberrant cytokine production, extramedullary hematopoiesis, and bone marrow fibrosis. Although somatic mutations in JAK2, MPL, and CALR have been identified in the pathogenesis of these diseases, inhibitors of t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Yue, Lanzhu, Bartenstein, Matthias, Zhao, Wanke, Ho, Wanting Tina, Han, Ying, Murdun, Cem, Mailloux, Adam W., Zhang, Ling, Wang, Xuefeng, Budhathoki, Anjali, Pradhan, Kith, Rapaport, Franck, Wang, Huaquan, Shao, Zonghong, Ren, Xiubao, Steidl, Ulrich, Levine, Ross L., Zhao, Zhizhuang Joe, Verma, Amit, Epling-Burnette, Pearlie K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374075/
https://ncbi.nlm.nih.gov/pubmed/28405618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90932
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky