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Efficacy of ALK5 inhibition in myelofibrosis
Myelofibrosis (MF) is a bone marrow disorder characterized by clonal myeloproliferation, aberrant cytokine production, extramedullary hematopoiesis, and bone marrow fibrosis. Although somatic mutations in JAK2, MPL, and CALR have been identified in the pathogenesis of these diseases, inhibitors of t...
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| Published in: | JCI Insight |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374075/ https://ncbi.nlm.nih.gov/pubmed/28405618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90932 |
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