Efficacy of ALK5 inhibition in myelofibrosis

Myelofibrosis (MF) is a bone marrow disorder characterized by clonal myeloproliferation, aberrant cytokine production, extramedullary hematopoiesis, and bone marrow fibrosis. Although somatic mutations in JAK2, MPL, and CALR have been identified in the pathogenesis of these diseases, inhibitors of t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Yue, Lanzhu, Bartenstein, Matthias, Zhao, Wanke, Ho, Wanting Tina, Han, Ying, Murdun, Cem, Mailloux, Adam W., Zhang, Ling, Wang, Xuefeng, Budhathoki, Anjali, Pradhan, Kith, Rapaport, Franck, Wang, Huaquan, Shao, Zonghong, Ren, Xiubao, Steidl, Ulrich, Levine, Ross L., Zhao, Zhizhuang Joe, Verma, Amit, Epling-Burnette, Pearlie K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374075/
https://ncbi.nlm.nih.gov/pubmed/28405618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90932
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