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Mesenchymal Cell Reprogramming in Experimental MPL(W515L) Mouse Model of Myelofibrosis

Myelofibrosis is an indicator of poor prognosis in myeloproliferative neoplasms (MPNs), but the precise mechanism(s) contributing to extracellular matrix remodeling and collagen deposition in the bone marrow (BM) niche remains unanswered. In this study, we isolated mesenchymal stromal cells (MSCs) f...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Han, Ying, Yue, Lanzhu, Wei, Max, Ren, Xiubao, Shao, Zonghong, Zhang, Ling, Levine, Ross L., Epling-Burnette, Pearlie K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279751/
https://ncbi.nlm.nih.gov/pubmed/28135282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166014
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