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Mesenchymal Cell Reprogramming in Experimental MPL(W515L) Mouse Model of Myelofibrosis

Myelofibrosis is an indicator of poor prognosis in myeloproliferative neoplasms (MPNs), but the precise mechanism(s) contributing to extracellular matrix remodeling and collagen deposition in the bone marrow (BM) niche remains unanswered. In this study, we isolated mesenchymal stromal cells (MSCs) f...

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發表在:PLoS One
Main Authors: Han, Ying, Yue, Lanzhu, Wei, Max, Ren, Xiubao, Shao, Zonghong, Zhang, Ling, Levine, Ross L., Epling-Burnette, Pearlie K.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279751/
https://ncbi.nlm.nih.gov/pubmed/28135282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166014
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