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MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

Objective: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...

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Bibliografiske detaljer
Main Authors: Akpınar, Timur Selçuk, Hançer, Veysel Sabri, Nalçacı, Meliha, Diz-Küçükkaya, Reyhan
Format: Artigo
Sprog:Inglês
Udgivet: Galenos Publishing 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781658/
https://ncbi.nlm.nih.gov/pubmed/24385746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.65807
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