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MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

Objective: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...

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Main Authors: Akpınar, Timur Selçuk, Hançer, Veysel Sabri, Nalçacı, Meliha, Diz-Küçükkaya, Reyhan
格式: Artigo
語言:Inglês
出版: Galenos Publishing 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781658/
https://ncbi.nlm.nih.gov/pubmed/24385746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.65807
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