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MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms

Objective: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...

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Detalhes bibliográficos
Main Authors: Akpınar, Timur Selçuk, Hançer, Veysel Sabri, Nalçacı, Meliha, Diz-Küçükkaya, Reyhan
Formato: Artigo
Idioma:Inglês
Publicado em: Galenos Publishing 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781658/
https://ncbi.nlm.nih.gov/pubmed/24385746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.65807
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