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MPL W515L/K Mutations in Chronic Myeloproliferative Neoplasms
Objective: The MPL gene encodes the thrombopoietin receptor. Recently MPL mutations (MPL W515L or MPL W515K) were described in patients with essential thrombocythemia (ET) and primary (idiopathic) myelofibrosis (PMF). The prevalence and the clinical importance of these mutations are not clear. In th...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Galenos Publishing
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781658/ https://ncbi.nlm.nih.gov/pubmed/24385746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.65807 |
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