Two activating mutations of MPL in triple‐negative myeloproliferative neoplasms

MPLW515K or W515L mutation plays an important role in the pathogenesis of myeloproliferative neoplasms (MPNs) through signaling molecules of the cytokine receptor axis. Besides MPLW515K or W515L, more than 30 atypical MPL mutations have been reported in patients who are negative for JAK2V617F, MPLW5...

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Vydáno v:Cancer Med
Hlavní autoři: Xie, Juan, Chen, Xiuhua, Gao, Feng, Hou, Ruixia, Tian, Tingting, Zhang, Yaofang, Fan, Lifang, Hu, Jinjun, Zhu, Guiyang, Yang, Wanfang, Wang, Hongwei
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718619/
https://ncbi.nlm.nih.gov/pubmed/31294534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2387
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