Molecular mechanisms associated with leukemic transformation of MPL-mutant myeloproliferative neoplasms

Somatic activating mutations in MPL, the thrombopoietin receptor, occur in the myeloproliferative neoplasms, although virtually nothing is known about their role in evolution to acute myeloid leukemia. In this study, the MPL T487A mutation, identified in de novo acute myeloid leukemia, was not detec...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Beer, Philip A., Ortmann, Christina A., Stegelmann, Frank, Guglielmelli, Paola, Reilly, John T., Larsen, Thomas S., Hasselbalch, Hans C., Vannucchi, Alessandro M., Möller, Peter, Döhner, Konstanze, Green, Anthony R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2010
Aiheet:
Brief Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995575/
https://ncbi.nlm.nih.gov/pubmed/20823136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.029306
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