Molecular mechanisms associated with leukemic transformation of MPL-mutant myeloproliferative neoplasms

Somatic activating mutations in MPL, the thrombopoietin receptor, occur in the myeloproliferative neoplasms, although virtually nothing is known about their role in evolution to acute myeloid leukemia. In this study, the MPL T487A mutation, identified in de novo acute myeloid leukemia, was not detec...

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Detalhes bibliográficos
Main Authors: Beer, Philip A., Ortmann, Christina A., Stegelmann, Frank, Guglielmelli, Paola, Reilly, John T., Larsen, Thomas S., Hasselbalch, Hans C., Vannucchi, Alessandro M., Möller, Peter, Döhner, Konstanze, Green, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995575/
https://ncbi.nlm.nih.gov/pubmed/20823136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.029306
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