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Mesenchymal Cell Reprogramming in Experimental MPL(W515L) Mouse Model of Myelofibrosis

Myelofibrosis is an indicator of poor prognosis in myeloproliferative neoplasms (MPNs), but the precise mechanism(s) contributing to extracellular matrix remodeling and collagen deposition in the bone marrow (BM) niche remains unanswered. In this study, we isolated mesenchymal stromal cells (MSCs) f...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Han, Ying, Yue, Lanzhu, Wei, Max, Ren, Xiubao, Shao, Zonghong, Zhang, Ling, Levine, Ross L., Epling-Burnette, Pearlie K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279751/
https://ncbi.nlm.nih.gov/pubmed/28135282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166014
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