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Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ
Maladaptive repair after AKI may lead to progressive fibrosis and decline in kidney function. Sphingosine 1-phosphate has an important role in kidney injury and pleiotropic effects in fibrosis. We investigated the involvement of sphingosine kinase 1 and 2 (SphK1 and SphK2), which phosphorylate sphin...
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| Publicat a: | J Am Soc Nephrol |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Nephrology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373443/ https://ncbi.nlm.nih.gov/pubmed/27799486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016030306 |
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