ENL links histone acetylation to oncogenic gene expression in AML

Cancer cells are characterized by aberrant epigenetic landscapes and often exploit chromatin machinery to activate oncogenic gene expression programs(1). Recognition of modified histones by “reader” proteins constitutes a key mechanism underlying these processes; therefore, targeting such pathways h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Wan, Liling, Wen, Hong, Li, Yuanyuan, Lyu, Jie, Xi, Yuanxin, Hoshii, Takayuki, Joseph, Julia, Wang, Xiaolu, Loh, Yong-Hwee E., Erb, Michael A., Souza, Amanda L., Bradner, James E., Shen, Li, Li, Wei, Li, Haitao, Allis, C. David, Armstrong, Scott A., Shi, Xiaobing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372383/
https://ncbi.nlm.nih.gov/pubmed/28241141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21687
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg