Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML

INTRODUCTION: AML1-ETO produced by t(8;21) abnomality has multiple effects on the leukemogenesis of acute myeloid leukemia (AML). SET domain, bifurcated 2 (SETDB2) can mediate gene silencing by trimethylation of the ninth lysine residue of histone H3 protein (H3K9) of the promoter and has been confi...

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Detaylı Bibliyografya
Yayımlandı:Cancer Manag Res
Asıl Yazarlar: Mu, Guangfu, Chen, Fangping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007814/
https://ncbi.nlm.nih.gov/pubmed/32099474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S227036
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