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Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML
INTRODUCTION: AML1-ETO produced by t(8;21) abnomality has multiple effects on the leukemogenesis of acute myeloid leukemia (AML). SET domain, bifurcated 2 (SETDB2) can mediate gene silencing by trimethylation of the ninth lysine residue of histone H3 protein (H3K9) of the promoter and has been confi...
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| Publicado en: | Cancer Manag Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007814/ https://ncbi.nlm.nih.gov/pubmed/32099474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S227036 |
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