ENL links histone acetylation to oncogenic gene expression in AML

Cancer cells are characterized by aberrant epigenetic landscapes and often exploit chromatin machinery to activate oncogenic gene expression programs(1). Recognition of modified histones by “reader” proteins constitutes a key mechanism underlying these processes; therefore, targeting such pathways h...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Wan, Liling, Wen, Hong, Li, Yuanyuan, Lyu, Jie, Xi, Yuanxin, Hoshii, Takayuki, Joseph, Julia, Wang, Xiaolu, Loh, Yong-Hwee E., Erb, Michael A., Souza, Amanda L., Bradner, James E., Shen, Li, Li, Wei, Li, Haitao, Allis, C. David, Armstrong, Scott A., Shi, Xiaobing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372383/
https://ncbi.nlm.nih.gov/pubmed/28241141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21687
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