An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

The induction of broadly HIV-1 neutralizing antibodies (bNAbs), capable of neutralizing various viral strains, by vaccination is challenging, but understanding how a subset of HIV-infected individuals develops bNAbs may guide immunization strategies. Here, we describe the isolation and characterizat...

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Bibliografiska uppgifter
I publikationen:Nat Microbiol
Huvudupphovsmän: van Gils, Marit J., van den Kerkhof, Tom L.G.M., Ozorowski, Gabriel, Cottrell, Christopher A., Sok, Devin, Pauthner, Matthias, Pallesen, Jesper, de Val, Natalia, Yasmeen, Anila, de Taeye, Steven W., Schorcht, Anna, Gumbs, Stephanie, Johanna, Inez, Saye-Francisco, Karen, Liang, Chi-Hui, Landais, Elise, Nie, Xiaoyan, Pritchard, Laura K., Crispin, Max, Kelsoe, Garnett, Wilson, Ian A., Schuitemaker, Hanneke, Klasse, Per Johan, Moore, John P., Burton, Dennis R., Ward, Andrew B., Sanders, Rogier W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372380/
https://ncbi.nlm.nih.gov/pubmed/27841852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.199
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