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An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

The induction of broadly HIV-1 neutralizing antibodies (bNAbs), capable of neutralizing various viral strains, by vaccination is challenging, but understanding how a subset of HIV-infected individuals develops bNAbs may guide immunization strategies. Here, we describe the isolation and characterizat...

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Publicado no:Nat Microbiol
Main Authors: van Gils, Marit J., van den Kerkhof, Tom L.G.M., Ozorowski, Gabriel, Cottrell, Christopher A., Sok, Devin, Pauthner, Matthias, Pallesen, Jesper, de Val, Natalia, Yasmeen, Anila, de Taeye, Steven W., Schorcht, Anna, Gumbs, Stephanie, Johanna, Inez, Saye-Francisco, Karen, Liang, Chi-Hui, Landais, Elise, Nie, Xiaoyan, Pritchard, Laura K., Crispin, Max, Kelsoe, Garnett, Wilson, Ian A., Schuitemaker, Hanneke, Klasse, Per Johan, Moore, John P., Burton, Dennis R., Ward, Andrew B., Sanders, Rogier W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372380/
https://ncbi.nlm.nih.gov/pubmed/27841852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.199
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