Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein

Misfolding and aggregation of alpha-synuclein (αsyn) resulting in cytotoxicity is a hallmark of Parkinson's disease (PD) and related synucleinopathies. The recent body of evidence indicates that αsyn can be released from neuronal cells by nonconventional exocytosis involving extracellular vesic...

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Publicado en:Front Neurosci
Autores principales: Delenclos, Marion, Trendafilova, Teodora, Mahesh, Divya, Baine, Ann M., Moussaud, Simon, Yan, Irene K., Patel, Tushar, McLean, Pamela J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371652/
https://ncbi.nlm.nih.gov/pubmed/28424577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00172
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