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A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo

Alpha synuclein (αsyn) aggregates are associated with the pathogenesis of Parkinson's disease and others related disorders. Although modulation of αsyn aggregation is an attractive therapeutic target, new powerful methodologies are desperately needed to facilitate in vivo screening of novel the...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Delenclos, Marion, Trendafilova, Teodora, Jones, Daryl R., Moussaud, Simon, Baine, Ann-Marie, Yue, Mei, Hirst, Warren D., McLean, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717311/
https://ncbi.nlm.nih.gov/pubmed/26834539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00511
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