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Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain()

Using microarray and bioinformatics, we examined the gene expression profiles in transgenic mouse hearts expressing mutations in the myosin regulatory light chain shown to cause hypertrophic cardiomyopathy (HCM). We focused on two malignant RLC-mutations, Arginine 58→Glutamine (R58Q) and Aspartic Ac...

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書誌詳細
出版年:Arch Biochem Biophys
主要な著者: Huang, Wenrui, Kazmierczak, Katarzyna, Zhou, Zhiqun, Aguiar-Pulido, Vanessa, Narasimhan, Giri, Szczesna-Cordary, Danuta
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370580/
https://ncbi.nlm.nih.gov/pubmed/26906074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.02.022
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