Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain()

Using microarray and bioinformatics, we examined the gene expression profiles in transgenic mouse hearts expressing mutations in the myosin regulatory light chain shown to cause hypertrophic cardiomyopathy (HCM). We focused on two malignant RLC-mutations, Arginine 58→Glutamine (R58Q) and Aspartic Ac...

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Bibliografiska uppgifter
I publikationen:Arch Biochem Biophys
Huvudupphovsmän: Huang, Wenrui, Kazmierczak, Katarzyna, Zhou, Zhiqun, Aguiar-Pulido, Vanessa, Narasimhan, Giri, Szczesna-Cordary, Danuta
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370580/
https://ncbi.nlm.nih.gov/pubmed/26906074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.02.022
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