Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

Anti-drug antibodies in hemophilia patients substantially complicate treatment. Their elimination through immune tolerance induction (ITI) protocols poses enormous costs, and ITI is often ineffective for factor IX (FIX) inhibitors. Moreover, there is no prophylactic ITI protocol to prevent anti-drug...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Herzog, Roland W., Nichols, Timothy C., Su, Jin, Zhang, Bei, Sherman, Alexandra, Merricks, Elizabeth P., Raymer, Robin, Perrin, George Q., Häger, Mattias, Wiinberg, Bo, Daniell, Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368425/
https://ncbi.nlm.nih.gov/pubmed/28153098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.009
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