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Animal Models of Hemophilia
The X-linked bleeding disorder hemophilia is caused by mutations in coagulation factor VIII (hemophilia A) or factor IX (hemophilia B). Unless prophylactic treatment is provided, patients with severe disease (less than 1% clotting activity) typically experience frequent spontaneous bleeds. Current t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713797/ https://ncbi.nlm.nih.gov/pubmed/22137432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394596-9.00006-8 |
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