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Targeting human SET1/MLL family of proteins

The SET1 family of proteins, and in particular MLL1, are essential regulators of transcription and key mediators of normal development and disease. Here, we summarize the detailed characterization of the methyltransferase activity of SET1 complexes and the role of the key subunits, WDR5, RbBP5, ASH2...

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Dades bibliogràfiques
Publicat a:Protein Sci
Autors principals: Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368065/
https://ncbi.nlm.nih.gov/pubmed/28160335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3129
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