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Targeting human SET1/MLL family of proteins

The SET1 family of proteins, and in particular MLL1, are essential regulators of transcription and key mediators of normal development and disease. Here, we summarize the detailed characterization of the methyltransferase activity of SET1 complexes and the role of the key subunits, WDR5, RbBP5, ASH2...

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Podrobná bibliografie
Vydáno v:Protein Sci
Hlavní autoři: Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368065/
https://ncbi.nlm.nih.gov/pubmed/28160335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3129
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