MeDeCom: discovery and quantification of latent components of heterogeneous methylomes

It is important for large-scale epigenomic studies to determine and explore the nature of hidden confounding variation, most importantly cell composition. We developed MeDeCom as a novel reference-free computational framework that allows the decomposition of complex DNA methylomes into latent methyl...

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Vydáno v:Genome Biol
Hlavní autoři: Lutsik, Pavlo, Slawski, Martin, Gasparoni, Gilles, Vedeneev, Nikita, Hein, Matthias, Walter, Jörn
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366155/
https://ncbi.nlm.nih.gov/pubmed/28340624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1182-6
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