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MeDeCom: discovery and quantification of latent components of heterogeneous methylomes
It is important for large-scale epigenomic studies to determine and explore the nature of hidden confounding variation, most importantly cell composition. We developed MeDeCom as a novel reference-free computational framework that allows the decomposition of complex DNA methylomes into latent methyl...
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| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5366155/ https://ncbi.nlm.nih.gov/pubmed/28340624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1182-6 |
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