Pharmacokinetic Modeling and Limited Sampling Strategies Based on Healthy Volunteers for Monitoring of Ertapenem in Patients with Multidrug-Resistant Tuberculosis

Ertapenem is a broad-spectrum carbapenem antibiotic whose activity against Mycobacterium tuberculosis is being explored. Carbapenems have antibacterial activity when the plasma concentration exceeds the MIC at least 40% of the time (40% T(MIC)). To assess the 40% T(MIC) in multidrug-resistant tuberc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: van Rijn, S. P., Zuur, M. A., van Altena, R., Akkerman, O. W., Proost, J. H., de Lange, W. C. M., Kerstjens, H. A. M., Touw, D. J., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J. W. C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365678/
https://ncbi.nlm.nih.gov/pubmed/28137814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01783-16
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