Pharmacokinetics of 2,000 Milligram Ertapenem in Tuberculosis Patients

Ertapenem is a carbapenem antibiotic with activity against Mycobacterium tuberculosis. Dose simulations in a hollow-fiber infection model showed that 2,000 mg once daily is an appropriate dose to be tested in clinical studies. Before using this dose in a phase II study, the aim of this prospective p...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Zuur, M. A., Ghimire, S., Bolhuis, M. S., Wessels, A. M. A., van Altena, R., de Lange, W. C. M., Kosterink, J. G. W., Touw, D. J., van der Werf, T. S., Akkerman, O. W., Alffenaar, J. W. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923177/
https://ncbi.nlm.nih.gov/pubmed/29439978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02250-17
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