Quantification and Validation of Ertapenem Using a Liquid Chromatography-Tandem Mass Spectrometry Method

Ertapenem, a carbapenem, relies on time-dependent killing. Therapeutic drug monitoring (TDM) should be considered, when ertapenem is used in specific populations, to achieve optimal bactericidal activity and optimize drug-dosing regimens. No validated liquid chromatography-tandem mass spectrometry (...

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Detalles Bibliográficos
Main Authors: van Rijn, S. P., Wessels, A. M. A., Greijdanus, B., Touw, D. J., Alffenaar, J. W. C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Analytical Procedures
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068466/
https://ncbi.nlm.nih.gov/pubmed/24733468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00025-14
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