Pharmacokinetics of Levofloxacin in Multidrug- and Extensively Drug-Resistant Tuberculosis Patients

Pharmacodynamics are especially important in the treatment of multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB). The free area under the concentration time curve in relation to MIC (fAUC/MIC) is the most relevant pharmacokinetic (PK)-pharmacodynamic (PD) parameter for predicting the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: van't Boveneind-Vrubleuskaya, Natasha, Seuruk, Tatiana, van Hateren, Kai, van der Laan, Tridia, Kosterink, Jos G. W., van der Werf, Tjip S., van Soolingen, Dick, van den Hof, Susan, Skrahina, Alena, Alffenaar, Jan-Willem C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527618/
https://ncbi.nlm.nih.gov/pubmed/28507117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00343-17
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