Population Pharmacokinetic Model and Limited Sampling Strategies for Personalized Dosing of Levofloxacin in Tuberculosis Patients

Levofloxacin is an antituberculosis drug with substantial interindividual pharmacokinetic variability; therapeutic drug monitoring (TDM) could therefore be helpful to improve treatment results. TDM would be more feasible with limited sampling strategies (LSSs), a method to estimate the area under th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: van den Elsen, Simone H. J., Sturkenboom, Marieke G. G., van't Boveneind-Vrubleuskaya, Natasha, Skrahina, Alena, van der Werf, Tjip S., Heysell, Scott K., Mpagama, Stellah, Migliori, Giovanni B., Peloquin, Charles A., Touw, Daan J., Alffenaar, Jan-Willem C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256746/
https://ncbi.nlm.nih.gov/pubmed/30373800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01092-18
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