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Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils

RNA interference has been considered as an effective gene silencing method in basic and preclinical investigations. The aims of the present study were to construct a lentiviral vector expressing a short hairpin RNA (shRNA) targeting the murine CC chemokine receptor 3 (mCCR3), and to investigate its...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Med Rep
Prif Awduron: Zhu, Xin-Hua, Liao, Bing, Xu, Yi, Liu, Ke, Huang, Yun, Huang, Quan-Long, Liu, Yue-Hui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364839/
https://ncbi.nlm.nih.gov/pubmed/28035394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.6085
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