Intron-specific shRNA-mediated downregulation of survivin and promotion of apoptosis in HeLa cells

Overexpression of the survivin gene contributes to tumorigenesis; it has been recognized as an important target for cancer therapy. In the present study, survivin expression was suppressed using recombinant plasmid mediated short hairpin RNAs (shRNAs) that were constructed to target exonic or intron...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wang, Yue-Li, Shao, Xin, Wang, Fa, Zeng, Liang, Hu, Liang, Cui, Shi-Quan, Hou, Gan, Huang, Di-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661408/
https://ncbi.nlm.nih.gov/pubmed/29113228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6996
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