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Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells

BACKGROUND: Survivin, a member of the inhibitor of apoptosis protein family, is highly expressed in many cancers and has important roles in inhibiting apoptosis by blocking caspase activation. However, its antitumor effects remain largely unknown. Here we explore the function of survivin in skin can...

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書目詳細資料
發表在:Onco Targets Ther
Main Authors: Hao, Yuqin, Bai, Xuefeng, Liu, Xia, Kang, Shuxia, Zhang, Xin, Liu, Caiyun, Li, Zhehai
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475095/
https://ncbi.nlm.nih.gov/pubmed/31118663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S162150
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