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Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils

RNA interference has been considered as an effective gene silencing method in basic and preclinical investigations. The aims of the present study were to construct a lentiviral vector expressing a short hairpin RNA (shRNA) targeting the murine CC chemokine receptor 3 (mCCR3), and to investigate its...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Zhu, Xin-Hua, Liao, Bing, Xu, Yi, Liu, Ke, Huang, Yun, Huang, Quan-Long, Liu, Yue-Hui
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364839/
https://ncbi.nlm.nih.gov/pubmed/28035394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.6085
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