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Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils

RNA interference has been considered as an effective gene silencing method in basic and preclinical investigations. The aims of the present study were to construct a lentiviral vector expressing a short hairpin RNA (shRNA) targeting the murine CC chemokine receptor 3 (mCCR3), and to investigate its...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhu, Xin-Hua, Liao, Bing, Xu, Yi, Liu, Ke, Huang, Yun, Huang, Quan-Long, Liu, Yue-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364839/
https://ncbi.nlm.nih.gov/pubmed/28035394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.6085
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