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Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy

Understanding the molecular processes characterizing Ewing sarcoma (EWS) cell migration is crucial to highlight novel therapies for patients with disseminated disease. In this study we analyzed the role of ROCK kinases in the regulation of cell migration, growth and differentiation of EWS cells. Ove...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Pinca, Rosa Simona, Manara, Maria Cristina, Chiadini, Valentina, Picci, Piero, Zucchini, Cinzia, Scotlandi, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364828/
https://ncbi.nlm.nih.gov/pubmed/28112365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5397
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