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Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy

Understanding the molecular processes characterizing Ewing sarcoma (EWS) cell migration is crucial to highlight novel therapies for patients with disseminated disease. In this study we analyzed the role of ROCK kinases in the regulation of cell migration, growth and differentiation of EWS cells. Ove...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Rep
Hauptverfasser: Pinca, Rosa Simona, Manara, Maria Cristina, Chiadini, Valentina, Picci, Piero, Zucchini, Cinzia, Scotlandi, Katia
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364828/
https://ncbi.nlm.nih.gov/pubmed/28112365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5397
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