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Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy

Understanding the molecular processes characterizing Ewing sarcoma (EWS) cell migration is crucial to highlight novel therapies for patients with disseminated disease. In this study we analyzed the role of ROCK kinases in the regulation of cell migration, growth and differentiation of EWS cells. Ove...

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Dettagli Bibliografici
Pubblicato in:Oncol Rep
Autori principali: Pinca, Rosa Simona, Manara, Maria Cristina, Chiadini, Valentina, Picci, Piero, Zucchini, Cinzia, Scotlandi, Katia
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364828/
https://ncbi.nlm.nih.gov/pubmed/28112365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5397
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