Polyphosphate nanoparticles on the platelet surface trigger contact system activation

Polyphosphate is an inorganic polymer that can potentiate several interactions in the blood coagulation system. Blood platelets contain polyphosphate, and the secretion of platelet-derived polyphosphate has been associated with increased thrombus formation and activation of coagulation factor XII. H...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Verhoef, Johan J. F., Barendrecht, Arjan D., Nickel, Katrin F., Dijkxhoorn, Kim, Kenne, Ellinor, Labberton, Linda, McCarty, Owen J. T., Schiffelers, Raymond, Heijnen, Harry F., Hendrickx, Antoni P., Schellekens, Huub, Fens, Marcel H., de Maat, Steven, Renné, Thomas, Maas, Coen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364341/
https://ncbi.nlm.nih.gov/pubmed/28049643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-734988
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