Polyphosphate nanoparticles on the platelet surface trigger contact system activation

Polyphosphate is an inorganic polymer that can potentiate several interactions in the blood coagulation system. Blood platelets contain polyphosphate, and the secretion of platelet-derived polyphosphate has been associated with increased thrombus formation and activation of coagulation factor XII. H...

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Udgivet i:Blood
Main Authors: Verhoef, Johan J. F., Barendrecht, Arjan D., Nickel, Katrin F., Dijkxhoorn, Kim, Kenne, Ellinor, Labberton, Linda, McCarty, Owen J. T., Schiffelers, Raymond, Heijnen, Harry F., Hendrickx, Antoni P., Schellekens, Huub, Fens, Marcel H., de Maat, Steven, Renné, Thomas, Maas, Coen
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364341/
https://ncbi.nlm.nih.gov/pubmed/28049643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-734988
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