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Interactions between Zinc and Allosteric Modulators of the Glycine Receptor
The glycine receptor is a pentameric ligand-gated ion channel that is involved in fast inhibitory neurotransmission in the central nervous system. Zinc is an allosteric modulator of glycine receptor function, enhancing the effects of glycine at nanomolar to low-micromolar concentrations and inhibiti...
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| Udgivet i: | J Pharmacol Exp Ther |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363777/ https://ncbi.nlm.nih.gov/pubmed/28087784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.239152 |
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