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Trifluoroacetate is an allosteric modulator with selective actions at the glycine receptor
Trifluoroacetic acid is a metabolite of the inhaled anesthetics halothane, desflurane and isoflurane as well as a major contaminant in HPLC-purified peptides. Ligand-gated ion channels, including cys-loop receptors such as the glycine receptor, have been the targets of peptide-based drug design and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372770/ https://ncbi.nlm.nih.gov/pubmed/22548713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.04.011 |
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