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Identification of Novel Specific Allosteric Modulators of the Glycine Receptor Using Phage Display
The glycine receptor (GlyR) is a member of the Cys-loop superfamily of ligand-gated ion channels and the major mediator of inhibitory neurotransmission in the spinal cord and brainstem. Many allosteric modulators affect the functioning of members of this superfamily, with some such as benzodiazepine...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906275/ https://ncbi.nlm.nih.gov/pubmed/20501662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.130815 |
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