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Trifluoroacetate is an allosteric modulator with selective actions at the glycine receptor

Trifluoroacetic acid is a metabolite of the inhaled anesthetics halothane, desflurane and isoflurane as well as a major contaminant in HPLC-purified peptides. Ligand-gated ion channels, including cys-loop receptors such as the glycine receptor, have been the targets of peptide-based drug design and...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tipps, Megan E., Iyer, Sangeetha V., Mihic, S. John
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372770/
https://ncbi.nlm.nih.gov/pubmed/22548713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.04.011
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