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Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks

The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-associated proteins) technology enables rapid and precise genome editing at any desired genomic position in almost all cells and organisms. In this study, we analyzed the impact of different repair templates on the frequency o...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Song, Fei, Stieger, Knut
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363683/
https://ncbi.nlm.nih.gov/pubmed/28624224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.02.006
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