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Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks

The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-associated proteins) technology enables rapid and precise genome editing at any desired genomic position in almost all cells and organisms. In this study, we analyzed the impact of different repair templates on the frequency o...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Song, Fei, Stieger, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363683/
https://ncbi.nlm.nih.gov/pubmed/28624224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.02.006
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