Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity

Kidney toxicity is a major problem both in drug development and clinical settings. It is difficult to predict nephrotoxicity in part because of the lack of appropriate in vitro cell models, limited endpoints, and the observation that the activity of membrane transporters which plays important roles...

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Vydáno v:Curr Chem Genom Transl Med
Hlavní autoři: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Steiner, Toni, Bourner, Maureen, Mitchell, Michael, Thompson, David C., Zhao, Bin, Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Open 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362976/
https://ncbi.nlm.nih.gov/pubmed/28401035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501711010019
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